Congrats! HCHS has two STS Regeneron Semi-Finalists!

1/12/2025

Soleil and Ashley are STS Regeneron Scholars! Congratulations and Good Luck moving forward!

Society for Science proudly announces the top 300 scholars in the Regeneron Science Talent Search 2025, the nation’s oldest and most prestigious science and math competition for high school seniors. The Regeneron Science Talent Search provides students a national stage to present original research and celebrates the hard work and novel discoveries of young scientists who are bringing a fresh perspective to significant global challenges. The 300 scholars and their schools will be awarded $2,000 each.

Scholars were chosen based on their outstanding research, leadership skills, community involvement, commitment to academics, creativity in asking scientific questions and exceptional promise as STEM leaders demonstrated through the submission of their original, independent research projects, essays and recommendations. The 300 scholars hail from 200 American and international high schools and homeschools in 33 states, Washington D.C., Hong Kong, Malaysia, and Switzerland

Hunter College High Schools is proud to announce that we have two Regeneron Scholars (semi-finalists, top 300)! We wish the best to seniors Solei W. and Ashley Z. as they progress through the STS competition with the next round being decided on January 23rd. Brief project descriptions follow.

Soleil W.'s project:

Mechanistic Insights Into Org 43553-Induced Energy Expenditure in vitro

I worked with a team of investigators at the Center for Translational Medicine and Pharmacology at the Icahn School of Medicine at Mount Sinai on the development of an innovative treatment for obesity. Our strategy focuses on activating the luteinizing hormone receptor (LHCGR) pathway in adipocytes (fat cells) with a medication called Org 43553, which we found increases intracellular energy expenditure and reduces fat accumulation. In collaboration with my mentor, my role in the project involved investigating the mechanisms underlying this pharmacologically induced fat loss, bringing us one step closer to providing a safe and effective treatment for obesity.

Ashley Z.'s project:

On Lobe Disappearance of n-Loop Curves Under Curve Shortening Flow:

Curve Shortening Flow (CSF) in differential geometry is a geometric flow that shrinks a curve in two-dimensional space so that every point on it moves in the inward normal direction at a speed proportional to its curvature. This project explores the properties of CSF on n-loop curves, expanding on a previous result by Angenent et al. and showing the uniqueness of a 3-loop curve for which all intersections are preserved under CSF within a particular family of curves. It additionally approximates the parameter space of the corresponding family of 5-loop curves and formulates a conjecture regarding the parameter spaces of n-loop curves for larger n.

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